Facile Cascaded Negative Magnetophoresis Chip Combined with ICP–MS for Efficient Sorting and Online Detection of Circulating Tumor Cells

and has the capability for direct downstream analysis and recultivation (cell viability of 99.27%). The method was applied for the detection of CTCs in real clinical blood samples from 10 patients diagnosed with various cancers, and the detection rate was 100%, providing a simple and efficient approach for clinical detection of rare CTCs.