Solubility Measurement and Modeling of 9-Phenylcarbazole in Various Organic Solvents at Different Temperatures toward Efficient Process Design of Solvent Antisolvent Precipitation

9-Phenylcarbazole (PCz) is widely used for synthesizing functional molecules in display material industry and synthetic crystal industry. This study aimed to gain reliable experimental data for PCz solubility in common organic solvents under atmospheric pressure in the temperature range of 278.15 to 313.15 K. The selected solvents are methanol, ethanol, n-propanol, isopropanol, n-butanol, n-hexane, cyclohexane, acetonitrile, 1,4-dioxane, tetrahydrofuran, dichloromethane, and trichloromethane. Evaluating the existing models for solid–liquid equilibrium showed that the Apelblat equation was reliable and that the maximum value of mean square deviation between experimental and calculated data was 0.016. This knowledge was referenced for designing the solvent antisolvent (SAS) precipitation processing. Purified products of PCz with a mass fraction purity of over 98.11% was obtained via SAS precipitation in a rotating packed bed with intensified micromixing. Bulk crystals of PCz with high quality were grown from acetonitrile via the deposited crystallization processing.