An Access to Chiral 3-Benzylchromanones and 2,6-Disubstituted Cyclohexanones via Rh-Catalyzed Chemo- and Enantioselective Hydrogenation of Arylidene Chromanones/Cyclohexanones†

A highly chemo- and enantioselective hydrogenation of arylidene chromanones/cyclohexanones catalyzed by the Rh-f-spiroPhos complex has been developed, providing a series of chiral 3-benzylchromanones in high yields (93−99%) with excellent enantioselectivities...