Visible‐Light‐Induced Acyl and Thiocyano Pyridylation of Alkenes with Aldehyde and NH4SCN

Abstract β‐pyridinyl ketones and β‐pyridinyl thiocyanates are commonly used as an essential organic synthesis intermediate and widely present in various drug molecules and bioactive molecules. Herein, a photoredox catalyzed acyl and thiocyano pyridylation of alkenes with aldehydes and NH 4 SCN via HAT and SET strategy respectively is described. This protocol employs more readily accessible aldehydes and NH 4 SCN as radical precursors under redox‐neutral conditions. Moreover, high atom economy, simple and accessible starting materials, late‐stage modification and wide substrate scope including primary, secondary alkyl aldehydes and aromatic aldehydes enable the potential application in the organic synthesis.