Combination of photothermia and magnetic hyperthermia properties of Fe3O4@Ag hybrid nanoparticles fabricated by seeded‐growth solvothermal reaction

Abstract In this work, the monodisperse Fe 3 O 4 @Ag core‐shell hybrid nanoparticles (NPs) with an average size of 16.0 nm have been successfully fabricated by the seeded‐growth method in the organic solvent. The influence of the molar ratios of AgNO 3 /OLA on the formation of hybrid NPs has been investigated in detail to find the optimal conditions for the synthesis of the desired Fe 3 O 4 @Ag hybrid NPs. The hydrophobic Fe 3 O 4 @Ag hybrid NPs were successfully transferred into the water using poly (maleic anhydride‐alt‐1‐octadecene) (PMAO). The PMAO coated Fe 3 O 4 @Ag nanoparticles were well dispersed and stable in water over a wide range of pH from 2 to 11 as well as reasonable electrolyte concentration. The Fe 3 O 4 @Ag magneto‐plasmonic design can efficiently combine magnetic hyperthermia into an effective bimodal thermo‐therapy.