Analyses of risk factors for posterior communicating artery aneurysm rupture

Objective To analyze the risk factors for posterior communicating artery (PCoA) aneurysm rupture from the clinical and morphological aspects. Methods Consecutive patients with single PCoA aneurysm admitted to hospital from January 2011 to December 2013 were analyzed retrospectively. The clinical data and imaging characteristics were analyzed with univariate analysis and multivariate logistic regression analysis. Results Univariate analysis indicated that there were significant differences in the rupture rate of PCoA aneurysms in the history of hypertension (χ2=23.013, P=0.000) , aspect ratio (AR) ≥1.5 (χ2=8.492, P=0.004), directions of different aneurysm tops (χ2=15.057, P=0.002), and aneurysm blebs (χ2=18.952, P=0.000) between the two groups. The results of multivariate logistic regression analysis were the history of hypertension (OR, 13.240, P=0.000), presence of aneurysm blebs (OR, 12.933, P=0.001), age less than 60 years (OR, 3.766, P=0.010), AR ≥1.5 (OR=4.997, P=0.001), and posterior-inferior-lateral directions of aneurysm tops (OR, 7.584, P=0.038). Conclusion The history of hypertension, presence of aneurysm blebs, age less than 60 years, AR ≥1.5 and posterior-inferior-lateral directions of aneurysm tops were the risk factors for PCoA aneurysm rupture. Key words: Intracranial aneurysm; Risk factors; Posterior communicating artery