石墨烯
纳米复合材料
X射线光电子能谱
化学
光催化
核化学
亚甲蓝
纳米颗粒
氧化物
纳米技术
透射电子显微镜
傅里叶变换红外光谱
催化作用
扫描电子显微镜
化学工程
材料科学
有机化学
复合材料
工程类
作者
Kavitha Ganesan,Jothi Vinoth Kumar,N. Abirami,R. Arulmozhi,Siranjeevi Ravichandran,Satish Ramalingam
标识
DOI:10.1016/j.arabjc.2020.06.033
摘要
Nanotechnology is an embryonic field that grips countless impacts on the drug delivery system. Nanoparticles as haulers increase the capability of target-specific drug delivery to many folds hence are used in the treatment of dreadful diseases such as cancer, diabetes, etc. This boom has aimed at, to synthesize Copper oxide nanoparticles (CuO-NPs) using Acalypha Indica leaf extract and then incorporated with graphene oxide (GO) to form GO-CuO nanocomposites. Secondly, to sightsee the photocatalytic activity of CuO-NPs and GO-CuO nanocomposites towards the decolorization of methylene blue-dye and to test its activity against HCT-116 Human colon cancer cell lines. Synthesized nanocomposites were characterized using FTIR, UV–vis, X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), X-ray Photoelectron Spectroscopy (XPS) and transmission electron microscopy (TEM) analysis. The photocatalytic studies revealed that synthesized nanocomposites have the efficiency to degrade methylene blue dye by 83.20% and cytotoxic activity was found to be 70% against HCT-116 Human colon cancer cell lines at 100 μg/ml. GO-CuO nanocomposites have appreciable activity towards cancer cell lines and photocatalytic activity when compared to nanoparticles as such.
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