结合
立体选择性
催化作用
化学
肽
组合化学
立体化学
有机化学
生物化学
数学
数学分析
作者
Greta Vastakaite,Claudio E. Grünenfelder,Helma Wennemers
标识
DOI:10.1002/chem.202200215
摘要
Catalytic stereoselective additions with maleimides are useful one-step reactions to yield chiral succinimides, molecules that are widespread among therapeutically active compounds but challenging to prepare when the maleimide is C-substituted. We present the tripeptide H-Pro-Pro-Asp-NHC
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