适体
化学
分析物
注意事项
纳米技术
表面改性
细胞因子
免疫系统
干扰素
γ干扰素
计算生物学
干扰素γ
免疫学
分子生物学
生物化学
色谱法
体外
医学
材料科学
护理部
物理化学
生物
作者
Manjoosha R Yerrapragada,Dileep Mampallil
出处
期刊:Talanta
[Elsevier]
日期:2022-08-01
卷期号:245: 123428-123428
被引量:5
标识
DOI:10.1016/j.talanta.2022.123428
摘要
Interferon (IFN)-γ is a cytokine secreted by immune cells. The elevated levels of IFN-γ are an early indicator of multiple diseases such as tuberculosis and autoimmune diseases. This short review focuses on different sensing methods based on optical, electrochemical, and mechanical principles. We explain how specific biorecognition molecules such as antibodies and aptamers are employed in the sensing methods. We also compare different surface functionalization methods and their details. Although the review gives an overview of only IFN-γ sensing, the same strategies can be applied to sensing other analytes with appropriate modifications.
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