医学
自身免疫
Graves眼病
炎症
格雷夫斯病
脂肪组织
细胞因子
疾病
免疫学
病理
内科学
标识
DOI:10.1056/nejmra0905750
摘要
This article reviews the mechanisms that lead to the development of Graves' ophthalmopathy. A central feature in its development is autoimmunity that involves not only T cells, B cells, and macrophages but also fibroblasts and adipose tissue within the orbit. Intraorbital cytokine-mediated inflammation also has a prominent role. These recent findings suggest new ways of treating this debilitating disease.
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