Serum adiponectin is related to resistin independent of adiposity

Adipocytokines secreted by adiposity and other tissues in known to have inflammatory and anti-inflammatory property. Adiponectin and resistin are two important adipokines and they have important role in obesity and chronic related diseases. This study was designed to determine the relationship between serum adiponectin as an anti-inflammatory cytokine with resistin as a pro-inflammatory cytokine in thirty six sedentary adult men aged 38-44 years and body mass index, 32.56 ± 4.54 Kg/m2. For this purpose, participants fasted overnight to provide blood specimens and venous blood samples were collected of subjects. Blood samples were analyzed for measuring serum adiponectin and resistin. All anthropometrical variables were also measured. Serum adiponectin was not related with each anthropometrical marker (p≥0.05). In contrast, we observed that serum resistin was positively related anthropometrical indexes (p˂0.05). Serum adiponectin concentrations were negatively correlated with resistin, independent of BMI or fat tissue (P=0.000, r=0.77). Based on these data, we conclude the relationship between adiponectin and resistin levels were independent of adiposity in obese men.