医学
抽动秽语综合征
过敏
疾病
哮喘
嗜酸性粒细胞
强迫症
免疫球蛋白E
过敏性结膜炎
共病
免疫学
皮肤病科
精神科
内科学
抗体
作者
Murat Yüce,Şükrü Nail Güner,Koray Karabekiroğlu,Saliha Baykal,Mehtap Kılıç,Recep Sancak,Aytül Karabekiroğlu
出处
期刊:PubMed
日期:2014-01-01
卷期号:18 (3): 303-10
被引量:14
摘要
To investigate the rate of allergic diseases including asthma, allergic rhinitis and eczema in children and adolescents diagnosed with obsessive-compulsive disorder (OCD) (n:26) and/or Tourette syndrome (TS) (n:32) [OCD plus TS, n:13] compared to control subjects (n:35) [total, n:80].The symptoms of any allergic disease were assessed using the ISAAC questionnaire form. Allergy diagnoses were made by a pediatric allergy specialist. Skin prick tests were applied, and IgE levels and eosinophil counts were measured.While only one-fifth of the control subjects had allergic diseases, more than half of the children with TS and/or OCD had comorbid allergic diseases. Positive skin prick tests were greater in OCD patients compared to control subjects. There were no significant differences between the groups in terms of eosinophil counts or IgE levels. Among the allergic diseases, while allergic rhinitis was diagnosed at significantly higher rates in TS patients, eczema was significantly higher in OCD patients compared to control subjects.This preliminary study shows an association between allergic diseases and TS and/or OCD. The results revealing differences in associations between types of allergic disease (rhinitis or eczema) and neuropsychiatric disorder (tic disorder or OCD) need to be investigated in further studies with higher numbers of participants, and immune markers should be examined.
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