ChemInform Abstract: Bifunctional Amino Sulfonohydrazide Catalyzed Direct Asymmetric Mannich Reaction of Cyclic Ketimines with Ketones: Highly Diastereo‐ and Enantioselective Construction of Quaternary Carbon Stereocenters.

Abstract A bifunctional amino sulfonohydrazide is shown to enhance reactivity and enantioselectivity in the direct asymmetric Mannich reaction of N‐sulfonyl cyclic ketimines with ketones.