先天免疫系统
免疫学
先天性淋巴细胞
生物
疾病
获得性免疫系统
免疫
炎症
免疫系统
细胞生物学
医学
病理
作者
Amine Toubal,Isabelle Nel,Sophie Lotersztajn,Agnès Lehuen
出处
期刊:Nature Reviews Immunology
[Springer Nature]
日期:2019-07-15
卷期号:19 (10): 643-657
被引量:205
标识
DOI:10.1038/s41577-019-0191-y
摘要
Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate and adaptive immunity. They are activated by conserved bacterial ligands derived from vitamin B biosynthesis and have important roles in defence against bacterial and viral infections. However, they can also have various deleterious and protective functions in autoimmune, inflammatory and metabolic diseases. MAIT cell involvement in a large spectrum of pathological conditions makes them attractive targets for potential therapeutic approaches.
科研通智能强力驱动
Strongly Powered by AbleSci AI