赫拉
化学
嘧啶
质子核磁共振
组合化学
碳-13核磁共振
元素分析
立体化学
宫颈癌
癌症
生物化学
有机化学
细胞
内科学
医学
作者
Dhananjay Pandya,Yogesh T. Naliapara
出处
期刊:Letters in Organic Chemistry
[Bentham Science]
日期:2020-03-25
卷期号:17 (4): 294-302
标识
DOI:10.2174/1570178616666190705152116
摘要
A series of novel 5H-Thiochromeno[4,3-d]pyrimidine derivatives were synthesized, purified and characterized by different spectroscopy techniques such as 1H NMR, 13C NMR, Mass and Elemental Analysis. The new compounds were evaluated for their anti-cervical cancer activity on Human Cervical Cell Line HeLa. They were found to be potent anti-cervical cancer agents with GI50 values less than 10 μg/mL with respect to positive control drug Adriamycin.
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