医学
内科学
肿瘤科
卵巢癌
化疗
分子生物标志物
临床试验
生物标志物
临床研究阶段
癌症
队列
上皮性卵巢癌
新辅助治疗
作者
F. Blanc-Durand,Benoit You,Yahia Adnani,Gaëtan De Rauglaudre,Isabelle Ray-Coquard,Pierre Combe,Cyril Abdeddaim,Florence Joly,G. Ferron,Clotilde Deldycke,Olivier Colomban,Marie-Christine Kaminsky,Jerome Meunier,J. Alexandre,Coriolan Lebreton,Laurence Venat,Laure Favier,C. Louvet,Sophie Abadie‐Lacourtoisie,Eric Pujade Lauraine
摘要
HRD status, KELIM, and TILs are key independent biomarkers in advanced OC. CCNE1 amplifications, although typically associated with platinum resistance, were linked to moderate chemotherapy sensitivity, defining an intermediate prognostic subgroup.
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