The role of aetiology in determining anticoagulation effectiveness for the treatment of left ventricular thrombus

The underlying aetiology of LV dysfunction significantly influences both treatment response and outcomes in patients with LV thrombus. DOAC were associated with superior efficacy and safety in AMI-related LV thrombus, but were linked to increased rates of SSE in NICM. These findings highlight the importance of aetiology on LV thrombus management and the potential need for tailored approaches.