The use of a silicone base under a total prosthesis makes possible the solution of certain problems of tolerance or maintenance of such denture. I.--Full denture in patients who have received radiotherapy. II.--Full denture with intolerant mucosa. III.--Following failure of classical prosthesis. IV--Prosthesis fitted following pre-prosthetic surgery. The technical problems associated with the fabrication of such prosthesis and possible adjustements are discussed.