Objective To explore the special correlation between Zusanli(ST 36)and stomach through observing the regulation function of electroacupuncture at Zusanli(ST 36)on microcirculation in normal rats.Methods Forty SD rats were randomized into normal control group,Sanyinjiao(SP 6)group Ⅰ and Ⅱ,and Zusanli(ST 36)group Ⅰ and Ⅱ,with 8 rats in each group.The normal control group,Sanyinjiao(SP 6)group Ⅰ,and Zusanli(ST 36)group Ⅰ were bound for 7 days,while the Sanyinjiao(SP 6)group Ⅱ and Zusanli(ST 36)group Ⅱ were treated with electroacupuncture for 7 days in succession.On the 8th day the microcirculation on the surface of stomach,duodenum,liver and brain was determined with the laser Doppler blood flow monitor.Results The microcirculation of stomach was significantly improved by electroacupuncture in all acupuncture groups compared with before treatment and the normal control group.The improvement of microcirculation in Zusanli(ST 36)group Ⅱ,was more significant than in Zusanli(ST 36)group Ⅰ and Sanyinjiao(SP 6)group Ⅱ(P0.05).The microcirculation of duodenum was significantly improved by electroacupuncture in Sanyinjiao(SP 6)group Ⅱ and Zusanli(ST 36)group Ⅱ(P0.05).Compared with the normal control group,the influence of acupuncture on microcirculation of liver and brain in all acupuncture groups was not significant(P0.05).Conclusion Microcirculation of stomach and duodenum can be effectively regulated by electroacupuncture at Zusanli(ST 36)of normal rats,indicating that specific correlation exist between Zusanli(ST 36)and stomach.