A Comparison of 10% Benzoyl Peroxide Cream and 5% Benzoyl Peroxide Gel in the Treatment of Acne Vulgaris

To evaluate the efficacy and safety of 10% benzoyl peroxide cream in the treatment of acne vulgaris, a randomized, effective controlled clinical trial was performed. 63 patients were given 10% benzoyl peroxide cream (imported) and the other 43 patients were given 5% benzoyl peroxide gel (domestic product). Both drugs were used on the surface of the skin 2 times a day for 6 weeks. The results showed that the curative rates and total effective rates were 30.2%, 85.7% and 14%, 62.8% in two groups respectively. The effective rates were much higher for 10% benzoyl peroxide cream than 5% benzoyl Peroxide gel (P0.05) The adverse reactions to both drugs were 17.2%, 33.0% respectively. The results suggest 10% benzoyl peroxide cream has a higher efficacy and safety than 5% benzoyl peroxide gel for the treatment of acne vulgaris.