Co(II),Fe(II) complexes of sulfadiazine and sulfamethoxazole were synthesized,respectively,and the structures of products were confirmed by IR spectra and elemental analysis.During the experiment,the water and methanol were selected as solvent to synthesize Co(II) Complex of sulfadiazine and sulfamethoxazole,and the bond model of the different products turn out to be the same.For the Fe(II) Complex of sulfadiazine and sulfamethoxazole,the solvent only is water.