Botanical description, ethnomedicinal uses, phytochemistry and pharmacological effects of Croton dichogamus Pax (Euphorbiaceae)

巴豆 传统医学 植物化学 大戟科 医学 抗菌剂 药理学 生物 植物 微生物学
作者
Dorine Nyak Matara,Joseph Mwanzia Nguta,Fredrick Mutie Musila,Isaac Ole Mapenay,Hashim Mohamed Ali,Vincent Mokoro Omambia
出处
期刊:The journal of phytopharmacology [BioMed Research Publishers]
卷期号:10 (1): 42-47 被引量:6
标识
DOI:10.31254/phyto.2021.10109
摘要

Croton dichogamus Pax (Euphorbiaceae) has been used widely in traditional ethnopharmacological practices against a wide number of ailments. The pharmacological activities, phytochemical composition and its safety aspects have been covered in a number of articles. The present review aims to provide a comprehensive literature overview regarding botanical description, phytochemical composition, local uses, pharmacology and toxicological effects of crude extracts, fractions and isolated compounds obtained using different solvent systems. The review was compiled through a thorough literature search from authentic resources using Google, Google Scholar, Medline, PubMed, Chemical abstracts, Web of Science, Scopus, Science Direct, peer reviewed articles, books and thesis. Croton dichogamus is an important ethnomedicinal plant used traditionally for the treatment of tuberculosis and other respiratory tract infections, stomach ache, fever, sexually transmitted diseases such as syphilis and gonorrhea, impotence, arthritis, tooth ache, infertility and malaria. Pharmacological and toxicological studies performed on the fresh plant parts and crude extracts prepared using different extraction solvents validates the ethnomedicinal utilization of Croton dichogamus. Studies performed validate the use of Croton dichogamus extracts in antimicrobial, antioxidative and antiproliferative therapy. Information on therapeutic validation in analgesia, hypertension, wound healing, gastrointestinal motility and diabetes mellitus is scanty. To further advance the local use of Croton dichogamus in the above-mentioned illnesses, there is an urgent need for further studies to validate the traditionally reported anecdotal efficacy and safety. Data on safety of various crude extracts of Croton dichogamus is also scanty. However, the available information on toxicology of Croton dichogamus suggests it is safe. The current review supports in part, the ethnomedicinal use of the medicinal plant. However, in-depth studies aimed at efficacy and safety evaluation, in addition to identification of compounds responsible for the reported activities is required. This information will support steps towards discovery of novel ligands with activity against illnesses reported above.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1851611453完成签到 ,获得积分10
1秒前
3秒前
3秒前
甘sir完成签到 ,获得积分10
4秒前
蒙太奇完成签到 ,获得积分10
4秒前
NancyDee完成签到,获得积分10
5秒前
细心的文轩完成签到 ,获得积分10
8秒前
10秒前
大胆秋灵发布了新的文献求助30
10秒前
远了个方发布了新的文献求助10
14秒前
传奇3应助点点点点采纳,获得10
16秒前
英姑应助简单平蓝采纳,获得10
18秒前
专注的采梦完成签到 ,获得积分10
19秒前
科目三应助九九采纳,获得30
21秒前
21秒前
TIX完成签到 ,获得积分10
24秒前
pray发布了新的文献求助10
25秒前
木木发布了新的文献求助10
26秒前
29秒前
安静饼干完成签到,获得积分10
30秒前
Lasse1992完成签到,获得积分10
30秒前
北岭雪兮发布了新的文献求助10
34秒前
远了个方完成签到,获得积分10
34秒前
香蕉觅云应助木木采纳,获得80
34秒前
亓亓完成签到 ,获得积分10
36秒前
乐乐应助ppxx采纳,获得20
36秒前
37秒前
38秒前
38秒前
优雅的怀莲完成签到,获得积分10
40秒前
简单平蓝发布了新的文献求助10
40秒前
chenlc971125完成签到 ,获得积分10
40秒前
zhangzhirong完成签到,获得积分10
43秒前
典雅问寒应助nini采纳,获得10
43秒前
Nhiii发布了新的文献求助10
45秒前
北岭雪兮完成签到 ,获得积分20
46秒前
zhangzhirong发布了新的文献求助10
46秒前
小郑在学习完成签到,获得积分10
46秒前
56秒前
北风完成签到 ,获得积分10
57秒前
高分求助中
【此为提示信息,请勿应助】请按要求发布求助,避免被关 20000
Continuum Thermodynamics and Material Modelling 2000
Encyclopedia of Geology (2nd Edition) 2000
105th Edition CRC Handbook of Chemistry and Physics 1600
Maneuvering of a Damaged Navy Combatant 650
Периодизация спортивной тренировки. Общая теория и её практическое применение 310
Mixing the elements of mass customisation 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3778363
求助须知:如何正确求助?哪些是违规求助? 3324059
关于积分的说明 10216978
捐赠科研通 3039300
什么是DOI,文献DOI怎么找? 1667944
邀请新用户注册赠送积分活动 798438
科研通“疑难数据库(出版商)”最低求助积分说明 758385