医学
优势比
脂肪肝
内科学
置信区间
牙缺失
逻辑回归
胃肠病学
人口
疾病
牙科
口腔健康
环境卫生
作者
Feng Qian,Kaiyu Fu,Qing Zhang,Li Liu,Guang Meng,Hongmei Wang,Xia Yang,Xue Bao,Yeqing Gu,Hongbin Shi,Shaomei Sun,Xing Wang,Ming Zhou,Qiyu Jia,Kun Song,Kaijun Niu
摘要
Long-term oral chronic inflammatory process is closely related to systemic inflammation, which is a main mechanism involved in non-alcoholic fatty liver disease (NAFLD). Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with NAFLD. This study evaluated the association between missing teeth and presence of NAFLD in a general population.A cross-sectional study of 24,470 adults was carried out from the Tianjin Chronic Low-grade Systemic Inflammation and Health Cohort Study. The self-reported number of missing teeth (excluding third molars) was recorded and classified into four categories: 0, 1-2, 3-5, and ≥6. The NAFLD was diagnosed by the liver ultrasonography. Associations were analysed by adjusted multivariable logistic regression.The multivariable-adjusted odds ratios (95% confidence interval) of NAFLD across the categories of missing teeth were as follows: in males, 1.00 (reference), 1.04 (0.93-1.16), 1.06 (0.90-1.24), and 1.40 (1.09-1.81) (p for trend = 0.04); in females, 1.00 (reference), 0.98 (0.83-1.15), 1.11 (0.90-1.37), and 1.07 (0.77-1.48) (p for trend = 0.45).The number of missing teeth was associated with a higher presence of NAFLD in males but not females.
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