Structural Characterization of a Microperoxidase Inside a Metal‐Directed Protein Cage

Caged to submission: The zinc-ion-directed assembly of tetrahedral protein cages (Zn30:CFMC-112) in a rhombohedral crystal lattice is presented. The histidine side chains and exposed hydrophobic groups lining up the cavities of these cages enabled a flexible c-type heme peptide fragment (a microperoxidase) to be immobilized within and its crystal structure to be determined at 1.9 Å resolution.