溶解
生物利用度
口腔
药物输送
剂型
药品
患者依从性
溶解试验
首过效应
材料科学
药理学
化学
牙科
色谱法
纳米技术
医学
有机化学
急诊医学
生物制药分类系统
作者
Pallavi Patil,Shweta Shrivastava,S Vaidehi,Patil Ashwini
出处
期刊:International journal of drug regulatory affairs
[Society of Pharmaceutical Tecnocrats]
日期:2018-02-12
卷期号:2 (2): 49-60
被引量:24
标识
DOI:10.22270/ijdra.v2i2.131
摘要
This review represents importance of mouth dissolving films as compared to other oral dosage forms. Fast dissolving oral drug delivery system are solid dosage form which disintegrate or dissolve within seconds when placed in the mouth without need of water or chewing. First developed fast dissolving dosage form in formulation and the rapid disintegrating properties were obtained through a special procedure or formulation modification, hence mouth dissolving film is proved to be better alternative in such cases. This fast dissolving drug delivery system is suited for the drugs which undergo high first pass metabolism and is used for improving bioavailability. Mouth dissolving film consists of thin oral strip; which release active ingredients immediately after uptake into oral cavity. In present investigation, an attempt has been made to develop oral fast dissolving film. Availability of larger surface area that leads to rapid disintegrating and dissolution in the oral cavity.
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