A new drug treating idiopathic pulmonary fibrosis:pirfenidone

Idopathic pulmonary fibrosis(IPF) is a disease caused by unknown reason.To date,there is no one drug to effectively treat the disease.Pirfenidone is an anti-inflammatory,anti-oxidant,and antifibrotic angent that inhibits transforming growth factor-β in vitro and changes collagen synthesis and accumulation,and inhibits proliferation and extracellular matrix expression.In a series of clinical trials,pirfenidone is a potential for the treatment of IPF.