[Objective]To evaluate the reduction of glucocorticoid dosage and period after systemically inhaling Budesonide among the moderate and severe asthma patients.[Methods]36 moderate and severe bronchia asthma patients were taken as the case group treated with Budesonide(2mg,Bid) inhalation,33 similar patients were taken as the control;observation was made on the patients' recovery and the reduction of glucocorticoid dosage and the patients' lung faction changes.[Results] The average systemic glucocorticoid intake periods in the case group and the control were(7.6±2.7) days and(12.8 4±3.7) days respectively.[Conclusion] Inhaling Budesonide after systemic glucocorticoid treatment could reduce the glucocorticoid dosage and period for the moderate and severe asthma patients,besides,it has no side effects and the necessity of oral glucocorticoid intake.