The detection and prevention of transcranial Doppler ultrasound in the delayed cerebral vasospasm for skull base tumors postoperative

Objective To seek for inspection method of vasospasm for skull base tumors postoperative and its prevention and treatment. Methods 74 cases of skull base tumors from January 2011 to January 2012 admitted to our department were divided into treatment group( 40 cases) and control group( 34 cases),according to whether nimodipine managed. TCD analyzer dynamic monitored the ipsilateral middle cerebral artery( MCA) blood flow velocity respectively on the preoperative day,the first day,the third day,the fifth day,the seventh day,and the fourteenth day postoperative,and measured extracranial internal carotid artery blood flow velocity slightly below the mandibular angle. Results There were 24 cases with vasospasm in two groups,transcranial Doppler ultrasound showed the average flow velocity in the middle cerebral artery ≥120 cm / s,of which 11 cases of blood flow velocity ≥200 cm / s. 9 cases occurred vasospasm in treatment group which accounted for 22. 5%; 15 cases occurred vasospasm in control group which accounted for 44. 1%. The difference of cerebral vasospasm number was statistically significant between the two groups( P 0. 05) Conclusion Our study shows that nimodipine can equally effective in prevent ing and treating the delayed cerebral vasospasm for skull base tumors postoperative by intraoperative lavage,intravenous and oral managed. An indicator of transcranial Doppler ultrasound can timely,accurate,non-invasive dynamic quantitative monitor the delayed cerebral vasospasm after skull base tumor operation,is conducive to early detection of vasospasm and severity,can be treated as a guide.