Qualitative composition and quantitative changes of phospholipids of the whole blood and membranes of white rats erythrocytes have been studied as affected by ukrinol. Regularities in the change of phylogenetically stabilized phospholipid-phospholipid relations in the studied biological systems have been found under the long-term effect of ukrinol on the organism. The ways of normalizing of the disturbed phospholipid metabolism under ukrinol intoxication are discussed.