聚二甲基硅氧烷
拉曼光谱
表面增强拉曼光谱
相关系数
偏最小二乘回归
检出限
材料科学
化学
色谱法
分析化学(期刊)
算法
计算机科学
纳米技术
机器学习
拉曼散射
光学
物理
作者
Huanhuan Li,Wenhui Geng,Zihan Zheng,Suleiman A. Haruna,Quansheng Chen
出处
期刊:Food Chemistry
[Elsevier]
日期:2023-08-01
卷期号:418: 135998-135998
被引量:9
标识
DOI:10.1016/j.foodchem.2023.135998
摘要
The misuse of chloramphenicol (CAP) has led to the development of drug-resistant strains that pose significant threats to public health. Here, we propose a universal flexible surface-enhanced Raman spectroscopy (SERS) sensor utilizing gold nanotriangles (AuNTs) and polydimethylsiloxane (PDMS) film for rapid detection of CAP in food samples. Initially, AuNTs@PDMS with unique optical and plasmonic properties were used to collect spectra of CAP. Afterward, four chemometric algorithms were executed and compared. Accordingly, random frog-partial least squares (RF-PLS) exhibited optimum results with correlation coefficient of prediction (Rp = 0.9802) and the lowest root-mean-square error of prediction (RMSEP = 0.348 µg/mL). Furthermore, the sensor's efficacy to detect CAP in milk samples was confirmed, and the findings were compatible with the conventional HPLC approach (P > 0.05). Therefore, the proposed flexible SERS sensor could effectively be used to monitor milk quality and safety.
科研通智能强力驱动
Strongly Powered by AbleSci AI