光催化
金黄色葡萄球菌
抗菌活性
光合作用
伤口愈合
氧化损伤
自愈
材料科学
大肠杆菌
抗生素
纳米技术
微生物学
细菌
化学
有机化学
医学
生物
外科
氧化应激
生物化学
催化作用
替代医学
病理
遗传学
基因
作者
Liehuang Zhu,Antian Huo,Yang Sun,Yanzhao Chen,Chongjiang Cao,Yueqin Zheng,Weiwei Guo
标识
DOI:10.1002/adhm.202302087
摘要
Bacterial infection poses a constant threat to human health. It is crucial to develop cost-effective and multifunctional solutions to combat bacteria. In this study, inspiration has been taken from artificial photosynthesis and a hydrogel containing a photocatalytic metal-organic cluster (MOC) has been creatively formulated for wound healing and antibacterial purposes. Complete photocatalytic cycles have been achieved by combining the oxidative Ti-center and the reductive Cu-center, in which reactive oxygen species (1 O2 and ·OH) have been generated. The MOC has the capability to eliminate Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) at a concentration of 40 µg mL-1 . In addition, the hydrogel formulation (H-MOC) has been applied to wounds infected with S. aureus, resulting in improved healing efficiency. This work presents an innovative approach to utilizing photocatalytic biomaterials as non-antibiotic medications.
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