| 标题 |
Effects of adipose-derived stem cells treatment in chronic leg ulcers. A phase II randomized clinical trial
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| 其它 |
Sibilla, M.G., Zollino, I., Zamboni, M. & Zamboni, P. International angiology 2018 Issue 17 Pages 2018-02 摘要开头：Background: Adipose tissue is a source of different type of stem cells (ASCs). We investigated safety and effects of ASCs in a phase II rand-omized clinical trial, in the feld of recalcitrant venous leg ulcer (VLU). In addition we evaluated a reproducible methodological approach to standardize the isolation, characterization and the clinical use of the ASCs for ulcer wound healing. Finally, the biological data were corre-lated with the clinical follow-up of the patients after treatment. Methods: Sixteen (16) patients affected by chronic venous leg ulcers were randomized. ASCs were harvested using Coleman's technique and inject-ed into the ulcers. |
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