医学
磁共振成像
背痛
放射科
癌症
轴
回顾性队列研究
队列
腰痛
优势比
逻辑回归
外科
病理
内科学
替代医学
作者
Kathryn R. Tringale,Natalie Gangai,Andrew Seng Boon Chua,Kendra Godwin,Gloria Guman,Ilya Laufer,Kathleen N S Cathcart,Eric Lis,Adam Schmitt,Chaya S. Moskowitz,Marina Chilov,Behroze Vachha
出处
期刊:Spine
[Ovid Technologies (Wolters Kluwer)]
日期:2023-08-21
标识
DOI:10.1097/brs.0000000000004803
摘要
This is a retrospective, cross-sectional study.The primary aim was to identify the diagnostic yield of spine MRI in detecting malignant pathology in cancer patients with back pain. We also sought to evaluate the role of MRI extent (i.e., regional vs. total) in identifying malignant pathology.No prior study has systematically investigated the yield of spine MRI in a large cohort of cancer patients.Spine MRI reports from 2017-2021 for back pain (acute and non-specified chronicity) in cancer patients were reviewed to identify clinically-relevant findings: malignant 1) epidural, 2) leptomeningeal, 3) intramedullary, 4) osseous disease, 5) fracture. Logistic regression was used to evaluate the association between MRI extent and presence of cancer-related findings. For patients with multiple MRIs, short-interval scans (≤4 mo) were evaluated to assess the yield of repeat imaging.At least one cancer-related finding was identified on 52% of 5,989 spine MRIs ordered for back pain and 57% of 1,130 spine MRIs ordered specifically for acute back pain. The most common pathology was malignant osseous disease (2,545; 43%). Across all 5 categories, most findings (77-89%) were new/progressive. Odds of identifying a finding were significantly higher with total versus regional spine MRIs (P<0.001). While only 14 patients had a positive regional MRI followed shortly by a positive total spine MRI, most of these repeat total spine MRIs (78%) identified findings outside the scope of the initial regional scan. 21 patients had both CT and MRI within 30 days of each other; 8 (38%) had compression fractures appreciated on MRI but not on CT.Our findings suggest imaging the total spine in cancer patients with back pain given higher odds of identifying malignant pathology and instances of capturing otherwise not visualized disease. Further work is warranted to confirm these findings.
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