焦虑
茶氨酸
心理健康
部分激动剂
红藻氨酸受体
医学
兴奋剂
精神分裂症(面向对象编程)
AMPA受体
NMDA受体
精神科
药理学
内科学
受体
绿茶
化学
食品科学
作者
Michał Łata,Beata Getka,Justyna Kwiecień,Kinga Przyborowska,Katarzyna Wiejak,Mateusz Rukat
标识
DOI:10.12775/jehs.2024.53.010
摘要
L-theanine is an amino-acid found in green tea (Camellia sinensis), a beverage consumed by people all around the world. Its chemical structure is similar to L-glutamic acid. L-theanine acts as an antagonist of AMPA and kainate receptors as well as partial co-agonist of the NMDA receptors. The application may be associated with several health benefits, such as improvements in cognition, reduction of stress and anxiety-like symptoms. Although the dosage of L-theanine in green tea, which is around 20 mg per tea, is not very likely to have meaningful impact on mental health, supplementation of doses 200-400 mg/day has shown some promising advantages.Despite some evidence towards beneficial impact of L-theanine on mental health, longer-term and larger cohort clinical studies are required in order to justify its application for patients suffering from such diseases as anxiety, depression, bipolar disorder, schizophrenia and sleep disorders. What is more, it is more possible to act as a therapy augmentation in particular cases, rather than conventional therapy replacement.
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