医学
糖尿病性视网膜病变
糖尿病
视网膜
视网膜病变
横断面研究
内科学
心脏病学
疾病
眼科
病理
内分泌学
作者
Andre Chateaubriand Campos,Eduardo Gomes Lima,Peter Karl Jacobsen,Louis Arnould,Simão Augusto Lottenberg,Renata Martins Maia,Lívia S Conci,Tomás Minelli,A Morato,Roberto Dantas Nery-Jr,César Higa Nomura,Pedro Rissoli,Sérgio Luís Gianotti Pimentel,Carlos Serrano
标识
DOI:10.1016/j.jdiacomp.2024.108721
摘要
To investigate the association between diabetic retinopathy (DR) and coronary artery disease (CAD) using coronary angiotomography (CCTA) and multimodal retinal imaging (MMRI) with ultra-widefield retinography and optical coherence tomography angiography and structural domain. Single-center, cross-sectional, single-blind. Patients with diabetes who had undergone CCTA underwent MMRI. Uni and multivariate analysis were used to assess the association between CAD and DR and to identify variables independently associated with DR. We included 171 patients, 87 CAD and 84 non-CAD. Most CAD patients were males (74 % vs 38 %, P < 0.01), insulin users (52 % vs 38 %, p < 0.01) and revascularized (64 %). They had a higher prevalence of DR (48 % vs 22 %, p = 0.01), microaneurysms (25 % vs 13 %, p = 0.04), intraretinal cysts (22 % vs 8 %, p = 0.01) and areas of reduced capillary density (46 % vs 20 %, p < 0.01). CAD patients also had lower mean vascular density (MVD) (15.7 % vs 16.5,%, p = 0.049) and foveal avascular zone (FAZ) circularity (0.64 ± 0.1 vs 0.69 ± 0.1, p = 0.04). There were significant and negative correlations between Duke coronary score and MVD (r = −0.189; p = 0.03) and FAZ circularity (r = −0,206; p = 0.02). CAD, DM duration and insulin use independently associated with DR. CAD patients had higher prevalence of DR and lower MVD. CAD, DM duration and insulin use were independently associated with DR.
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