Biomimetic Bimetallic‐Polyphenol Network as a Novel siRNA Carrier for the Treatment of Rheumatoid Arthritis via Macrophage Repolarization

can further protect cartilage. In the collagen-induced arthritis (CIA) mouse model, TSSC@M1 can accumulate at inflamed joints and alleviate RA symptoms by modulating macrophage phenotype and repairing cartilage. Overall, TSSC@M1 NPs offer a promising and safe approach to treat RA.