N‐Heterocyclic Olefin‐Phosphines Based Cationic Ruthenium Complexes as Pre‐Catalysts for Dual C‐H Bond Functionalizations

Two N‐heterocyclic olefin‐phosphines and the corresponding ruthenium complexes were synthesized and structurally characterized. One of the cationic complexes [(BzIM)(NHOP)Ru(p‐cymene)Cl2]I was employed as a catalyst in N‐benzylbenzamides/alkyne coupling reactions. With this catalytic protocol a variety of substituted isoquinolones were synthesized through ortho‐selective double C‐H bond functionalization involving oxidative annulation followed by olefination reactions. All these products were achieved in one‐pot manner without the use of additives.