医学
肿瘤科
头颈部鳞状细胞癌
头颈部癌
内科学
疾病
人类免疫缺陷病毒(HIV)
放射治疗
癌症
头颈部
外科
免疫学
作者
Nurudeen Adebola Shofoluwe,Halima Aliyu,Balarabe Kabir,Ibrahim Babatunde Mohammed,Manir Anka Hamza,Amina Mohammed Abdullahi,Saadat Titilayo Yahaya
出处
期刊:Journal of the West African College of Surgeons
[Medknow Publications]
日期:2024-07-18
标识
DOI:10.4103/jwas.jwas_141_23
摘要
Patients diagnosed with head and neck squamous cell carcinoma (HNSCC), particularly those seropositive for human immunodeficiency virus (HIV), face a heightened risk of second primary malignancies (SPMs), with common regions being the head, neck, lung, and oesophagus. This risk amplifies the severity of their clinical condition, as these SPMs contribute significantly to the mortality rates in patients with HNSCC. We detail a case of a young woman, seropositive for HIV, who developed a second squamous cancer in the nasopharynx after achieving remission from her initial oropharyngeal squamous cell carcinoma through chemo-radiotherapy. This case study highlights the increased vulnerability of HIV-positive HNSCC patients to SPMs, with an observed association of HIV infection leading to a lower overall survival rate. As a result, we recommend long-term follow-up in HNSCC patients with HIV for early detection of SPMs. Our findings emphasize the importance of regular screening for HNSCC, particularly in people living with HIV, to ensure timely detection and treatment, which can significantly improve their prognosis.
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