Selectfluor™-catalyzed oxidative cyclization of ynamides enables facile synthesis of oxazolidine-2,4-diones

A Selectfluor™-catalyzed oxidative cyclization of ynamides employing DMSO as the solvent and oxidant was achieved, affording oxazolidine-2,4-diones in moderate to excellent yields with high chemo-selectivity. The method offers an attractive alternative to existing protocols.