生物气溶胶
拉曼光谱
粒子(生态学)
气溶胶化
材料科学
气溶胶
光谱学
纳米技术
光学
化学
物理
海洋学
地质学
有机化学
解剖
医学
吸入
量子力学
作者
Yukai Ai,Haifa Alali,Yong‐Le Pan,Gorden Videen,Chuji Wang
标识
DOI:10.1088/1361-6501/abd5f1
摘要
Abstract The detection and identification of bioaerosol particles, especially a potential threat from aerosolized biowarfare agents (BWAs), has become increasingly important. Here, we report on single-particle optical-trapping Raman spectroscopy (OT-RS) for the detection and identification of airborne biological particles. OT enables the capture of single particles in air for several minutes or longer, more than sufficient to capture the Raman spectra and minimize the interference from background aerosol particles. Simultaneously, the embedded imaging system can provide real-time information on the shape and size of the trapped particles. Several kinds of bioaerosol particles were analyzed using OT-RS including four BWA surrogates: Bacillus globigii, Yersinia rhodei , MS2, and Bacillus subtilis , along with some interfering bioaerosol particles commonly presented in the atmosphere. Similarities and differences of the Raman spectra of these biological particles are discussed. In addition, the BWA surrogates are well classified by using the principal component analysis. The results demonstrate that single-particle OT-RS can be used not only for the potential detection of BWAs but also for the identification of BWAs.
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