Highly sensitive nonenzymetic glucose sensing based on multicomponent hierarchical NiCo-LDH/CCCH/CuF nanostructures

A highly sensitive nonenzymetic electrochemical glucose sensor was developed by using a multicomponent sensing electrode made of nickel cobalt layered double hydroxide (NiCo-LDH) and cobalt copper carbonate hydroxide (CCCH) hierarchical nanostructure on Cu foam (NiCo-LDH/CCCH/CuF). The results of electrochemical measurements show that both the large accessible surface area of hierarchical nanostructure and the good conductivity of Cu foam are in favor of electrocatalysis so that the glucose detection. We have systematically evaluated the catalytic performance of NiCo-LDH/CCCH/CuF systems by changing the Ni:Co mole ratio and the synthesis time based on both cyclic voltammetry and amperometry techniques. Our results indicate that the optimization NiCo-LDH/CCCH/CuF system exhibits high sensitivity (10.78 μA/μM/cm2), large linear concentration range (0.0011.5 mM) and fast response-recovery times (2.4 s and 2.0 s) for glucose analyses. By integrating the NiCo-LDH/CCCH/CuF glucose sensing electrode with the custom-printed circuit board (PCB), we also demonstrate the feasibility of glucose detection at micromole level. Therefore, the NiCo-LDH/CCCH/CuF hierarchical nanostructure is applicable to the high sensitivity glucose determination.