医学
朗格汉斯细胞组织细胞增多症
女孩
脑膜炎
组织细胞增多症
皮肤病科
发育不良
病理
儿科
疾病
心理学
发展心理学
作者
Katsuhiko Kitazawa,Marika Matsumoto,Masayoshi Senda,Akihito Honda,Noriko Morimoto,Nobuko Kawashiro,Shinsaku Imashuku
摘要
Abstract We report a case of a girl with Langerhans cell histiocytosis (LCH) of multifocal bone disease, who developed recurrent bacterial meningitis and unilateral sensorineural hearing loss during the relapsing course of the disease. Mondini dysplasia, a congenital inner ear anomaly, was suspected by high resolution computed tomographic scan and the dysplasia with cerebrospinal fluid leakage was confirmed by surgery in the ipsilateral ear showing hearing loss. Although rare, congenital inner ear anomalies such as Mondini dysplasia should be kept in mind in pediatric patients with hearing impairment and/or recurrent bacterial meningitis during chemotherapy for various types of neoplasms including LCH. © 2004 Wiley‐Liss, Inc.
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