脱氧核酶
核酸外切酶
核酸外切酶 III
剧目
适体
解耦(概率)
细胞生物学
化学
信号(编程语言)
生物
DNA
计算生物学
分子生物学
HEK 293细胞
劈理(地质)
遗传学
生物物理学
核酸内切酶
基因复制
脱氧核糖核酸酶ⅰ
作者
Shusen Xiao,Kai Niu,Yangyang Chang,Zijie Zhang,Hong Yuan,Rui Zhang,Ying Zhang,Rudi Liu,Jiuxing Li,Meng LIU
摘要
We present an aptamer-gated exonuclease signal amplification (AGESA) strategy decoupling target recognition from DNAzyme activation to overcome background limitations, enabling selective detection of platelet-derived growth factor BB in urine and unlocking the DNAzyme repertoire for protein biomarkers.
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