Age-Adjusted PI-LL Versus L1 Pelvic Angle for Discriminating Proximal Junctional Kyphosis in Lower Thoracic Fusion for Adult Spinal Deformity

医学 后凸 骶骨 接收机工作特性 椎骨 脊柱畸形 脊柱融合术 腰椎前凸 核医学 畸形 前凸 腰椎 外科 并发症 脊柱侧凸 骨盆倾斜 解剖 盆腔 矢状面 腰椎 骨盆 固定(群体遗传学) 偏移量(计算机科学) 放射科
作者
Se‐Jun Park,Tae Soo Shin,Jin-Sung Park,Dong-Ho Kang,Jun-Seok Oh,Chong-Suh Lee
出处
期刊:Neurosurgery [Lippincott Williams & Wilkins]
标识
DOI:10.1227/neu.0000000000004296
摘要

BACKGROUND AND OBJECTIVES: Proximal junctional kyphosis (PJK) is a prevalent complication after adult spinal deformity surgery. Age-adjusted pelvic incidence minus lumbar lordosis (PI-LL) and L1 pelvic angle (L1PA) have both been proposed as lumbar correction targets, but their relative discriminative value for PJK has not been directly compared. METHODS: We retrospectively analyzed 373 patients who underwent fusion to the sacrum for adult spinal deformity with an uppermost instrumented vertebra between T9 and L1. PJK was defined as a proximal junctional angle of 20° or greater at 2 years or revision for proximal junctional complications. Each offset was the measured postoperative value minus its target value ([age -55]/2 + 3 for age-adjusted PI-LL; 0.5 × pelvic incidence -21 for L1PA), with negative values indicating a measurement below target. Directional agreement was assessed, and discrimination was evaluated with unadjusted restricted cubic spline and nested multivariable models adjusted for 10 clinical confounders, comparing areas under the receiver operating characteristic curve by the DeLong test. RESULTS: PJK developed in 133 patients (35.7%), and the 2 offsets correlated moderately (r = 0.535). Among 243 patients with a negative age-adjusted PI-LL offset, 181 (74.5%) did not have a negative L1PA offset; the reverse occurred in only 9 of 71 (12.7%) (P < .001). A negative L1PA offset was associated with PJK (50.7% vs 32.1%, P = .005), whereas a negative age-adjusted PI-LL offset was not (37.9% vs 31.5%, P = .271). Adding either offset improved discrimination over the base model (areas under the receiver operating characteristic curve 0.678-0.713 and 0.721, P = .031 and .017), but the 2 models did not differ (P = .643). CONCLUSION: The 2 indices discriminated PJK comparably, but only a negative L1PA offset identified patients at increased risk. When the 2 targets conflict, the L1PA target can be used as the more informative boundary.

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