Kounis综合征
医学
急性冠脉综合征
过敏反应
氨苄西林
阿莫西林
心肌梗塞
冠状动脉痉挛
过敏
麻醉
哮喘
心绞痛
内科学
青霉素
抗生素
免疫学
生物
微生物学
作者
Tahir Bezgin,Çetin Geçmen,Birol Özkan,Gökhan Alıcı,Mehmet Emin Kalkan,Ramazan Kargin,Ali Metin Esen
出处
期刊:Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners
日期:2013-03-23
被引量:8
标识
DOI:10.5830/cvja-2012-077
摘要
The concurrence of acute coronary syndrome with allergy or hypersensitivity as well as with anaphylactic or anaphylactoid reactions is increasingly encountered in daily clinical practice. There are several reports associating mast cell activation with acute cardiovascular events in adults. This was first described by Kounis as 'allergic angina syndrome',progressing to 'allergic myocardial infarction'. The main mechanism proposed is the vasospasm of coronary arteries. We present a case of a 28-year-old man who was admitted to our hospital with thoracic pain and dyspnoea. The symptoms recurred after simultaneous use of 1 g amoxicillin/clavulanic acid orally and 1 g ampicillin/sulbactam parenterally for tonsillitis the night before presentation and on the morning of admission.
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