Hyperchloremia Is Associated With Acute Kidney Injury in Patients With Subarachnoid Hemorrhage.

Objective To assess the prevalence of acute kidney injury in patients with subarachnoid hemorrhage patients. Design Retrospective analysis of all subarachnoid hemorrhage admissions. Settings Neurocritical care unit. Patients All patients with a diagnosis of subarachnoid hemorrhage between 2009 and 2014. Interventions None. Measurements and main results Of 1,267 patients included in this cohort, 16.7% developed acute kidney injury, as defined by Kidney Disease Improving Global Outcome criteria (changes in creatinine only). Compared to patients without acute kidney injury, patients with acute kidney injury had a higher prevalence of diabetes mellitus (21.2% vs 9.8%; p Conclusions Critically ill patients with subarachnoid hemorrhage show a strong association between hyperchloremia and acute kidney injury as well as acute kidney injury and mortality.