Objective :To study the accumulation of phenylpropanoid in different organs Changium syrnioides Wolff. Methods :The contents of p-methoxy cinnamic acid and 7-hydroxy coumarin in different organs of Changium smyrnioides Wolff were determined by HPLC method. Results :P-methoxy cinnamic acid and 7-hydroxy coumarin exist in various organs. The contents of p-methoxy cinnamic acid were the highest in roots,the contents of 7-hydroxy coumarin were the highest in flowers. Conclusion :HPLC methods were developed for the determination of p-methoxy cinnamic acid and 7-hydroxy coumarin(precursor composition of furocoumarin),providing the foundation for studying the biosynthesis of coumarin.