Chemical constituents from Lagotis brevituba

To study on the chemical consitituents of Lagotis brevituba.The chemical consitituents were isolated by silica gel column chromatography, polyamide column chromatography and semi-preparative HPLC, and their structures were identified by spectroscopic methods.Eight compounds were isolated and they were identified as beta-sitosterol (1), succinic acid (2), luteolin-7-O-beta-D-glucoside (3), uracil (4), apigenin (5), chrysoeriol (6), chrysoeriol-7-O-beta-D-glucoside (7), and apigenin-7-O-beta-D-glucoside (8).Compound 4-8 were isolated from L. brevituba for the first time, and among them, compound 7 and 8 were isolated from genus Lagotis for the first time.