Effect of Huanglongtang on Intestinal Motility in Animals

Objective:To investigate the effect of Huanglongtang on intestinal motility of experimental animals.Methods:The way of intact intestinal motility was used to measure time to start defecation and frequency of defecation and intestines moved forward.Isolated intestinal kinesis was used to measure duodenrm,ileum and colon kinesis in animals.Results:Defecation time was moved up and the frequency increased,and it did not take shape.Huanglongtang promoted strikingly intact intestines and isolated ileum motility in animals.There was inhibition to duodenum and colon in vitro in animals by taking Huanglongtang.The inhibition could be antagonized transiently by Ach.Conclusion:Huanglongtang has an outstanding purgative action in animals,which could be as a result of enhancement intestinal motility.The inhibition on isolated dudenum and colon showes that Huanglongtang has an antispasmodic effect while it purges.