Preparation and properties of electrochemical sensor for chlorogenic acid based on molecular imprinted polymers

An electrochemical sensor based on melorcularly imprinted films for chlorogenic acid(CGA)detection is reported.The sensor was prepared by electropolemerizing o-phenylenediam-ine(OPD) on a glassy carbon electrode in the presence of template chlorogenic acid.Differential pulse voltammetry was applied to investigate the analytical characteristics of the sensor,and indirect analytical method based on K3[Fe(CN)6]which is as electron transfer medium was established.The results indicate that the method has high selectivity and sensitivity,the relative peak current of sensor shows a linear dependance on the concentration of chlorogenic acid in the range of 8.0 × 10-7~ 2.0 × 10-5mol/L,with the detection limit of 1.4 × 10-7mol/L.This sensor was successfully applied to determination of chlorogenic acid in qinggan lidan oral liquid samples with recoveries ranging from 101.6% to 105.5%.